Born in West Orange, New Jersey, and raised in Denville Township, San Giacomo discovered acting early and later trained at Carnegie Mellon’s School of Drama. Her breakout role came in 1989’s Sex, Lies, and Videotape, which won the Palme d’Or at Cannes and earned her a Golden Globe nomination. Soon after, she left a lasting impression as Kit De Luca in Pretty Woman, blending grit, humor, and heart in a role audiences still remember.

During the early 1990s, she balanced indie films and mainstream projects, building a reputation for portraying complex characters. Then life changed. After becoming a mother to her son Mason, who was born with cerebral palsy, she shifted her priorities. Advocacy for disability awareness and inclusive education became central to her life, earning recognition from major organizations.

Professionally, she moved into television, starring as Maya Gallo in Just Shoot Me! for seven seasons and later appearing in series such as NCIS and Veronica Mars. Now 63, San Giacomo lives in California, still active in acting and advocacy. Her story isn’t about stepping away from Hollywood — it’s about redefining success, balancing career, family, and purpose on her own terms.